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C Feinle
a Department of
Internal Medicine, Division of Gastroenterology, University Hospital
Zürich, Switzerland, b Institute of Biomedical Engineering and
Medical Informatics, University/ETH Zürich, Switzerland
Correspondence to: Dr C Feinle, Department of Internal Medicine, Division of
Gastroenterology, University Hospital Zürich, Rämistr. 100, 8091 Zürich, Switzerland. Accepted for publication 7 July 1998
Background Keywords:
magnetic resonance imaging;
scintigraphy;
gastric
emptying;
solid meal;
liquid meal
We have previously used
a magnetic resonance imaging (MRI) method to study gastric emptying of
liquids. So far, however, it has not possible to assess solid gastric
emptying with this technique.
AimsTo validate scintigraphically
MRI as a method for measuring emptying of a mixed solid/liquid meal.
MethodsIn eight healthy subjects,
gastric emptying of a solid/liquid (SM) and a liquid meal (LM) of
identical energy content and macronutrient composition was studied by
scintigraphy and MRI for 120 minutes.
ResultsMRI and scintigraphy agreed
with respect to emptying profiles (intraclass correlation
coefficient (RI) SM: 0.988, RI, LM:
0.917), t1/2 (SMMRI: 129 (9),
SMScinti: 123 (11) minutes, NS; LMMRI: 100 (7),
LMScinti: 110 (8) minutes, NS) and AUC (SMMRI:
8999 (232), SMScinti: 8788 (277) min%, NS;
LMMRI: 8819 (368), LMScinti: 8891 (321) min%, NS).
ConclusionsMRI can be used to
measure reliably gastric emptying not only of liquid but also of mixed
solid/liquid meals in humans.
(GUT 1998;44:106-111)
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