HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Szurszewski, J H Articles by Miller, S M Search for Related Content PubMed PubMed Citation Articles by Szurszewski, J H Articles by Miller, S M

Prevertebral ganglia and intestinofugal afferent neurones

Department of Physiology and Biophysics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, 55905 USA

Correspondence to:
Correspondence to:
Dr J H Szurszewski, Department of Physiology and Biophysics, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA;
gijoe{at}mayo.edu

ABSTRACT
Intestinofugal afferent neurones (IFANs) are a unique subset of myenteric ganglion neurones that regulate normal gastrointestinal function. The IFANs relaying mechanosensory information to sympathetic neurones of the prevertebral ganglion (PVG) function as volume detectors. It is possible that mechanosensory information arriving in the PVG via axon collaterals of visceral spinal afferent nerves can be modulated entirely within the PVG itself.

Keywords: prevertebral ganglia; sympathetic neurones; intestinal afferent nerves; mechanosensitivity

Abbreviations: CGRP, calcitonin gene related peptide; F-EPSP, fast excitatory postsynaptic potential; GABA, gamma aminobutyric acid; IFAN, intestinofugal afferent neurone; IMA, intramuscular array; IMG, inferior mesenteric ganglion; IPAN, intrinsic primary afferent neurone; PVG, prevertebral ganglion; S-EPSP, slow excitatory postsynaptic potential; SMG, superior mesenteric ganglion; SP, substance P; VIP, vasoactive intestinal peptide

This article has been cited by other articles:

				C. Y. Liu, M. H. Mueller, D. Grundy, and M. E. Kreis Vagal modulation of intestinal afferent sensitivity to systemic LPS in the rat Am J Physiol Gastrointest Liver Physiol, May 1, 2007; 292(5): G1213 - G1220. [Abstract] [Full Text] [PDF]

				S. K. Sarna Molecular, functional, and pharmacological targets for the development of gut promotility drugs Am J Physiol Gastrointest Liver Physiol, October 1, 2006; 291(4): G545 - G555. [Abstract] [Full Text] [PDF]

				L. G Ermilov, P. F Schmalz, S. M Miller, and J. H Szurszewski PACAP modulation of the colon-inferior mesenteric ganglion reflex in the guinea pig J. Physiol., October 1, 2004; 560(1): 231 - 247. [Abstract] [Full Text] [PDF]