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Dark lumen magnetic resonance colonography: comparison with conventional colonoscopy for the detection of colorectal pathology

Department of Diagnostic and Interventional Radiology, University Hospital, Essen, Germany

Correspondence to:
Correspondence to:
Dr W Ajaj
Hufelandstr 55, Essen 45122, Germany; waleed.ajaj{at}uni-essen.de

ABSTRACT
Background: The purpose of this study was to assess the feasibility and usefulness of a new magnetic resonance (MR) colonography technique for the detection of colorectal pathology in comparison with conventional colonoscopy as the standard of reference.

Patients and methods: A total of 122 subjects with suspected colorectal disease underwent "dark lumen" MR colonography. A contrast enhanced T1w three dimensional VIBE sequence was collected after rectal administration of water. The presence of colorectal masses and inflammatory lesions were documented. Results were compared with those of a subsequently performed colonoscopy.

Results: MR colonography was found to be accurate regarding detection of clinically relevant colonic lesions exceeding 5 mm in size, with sensitivity and specificity values of 93%/100%.

Conclusion: Dark lumen MR colonography can be considered as a promising alternative method for the detection of colorectal disease. In addition, it allows assessment of extraluminal organs.

Keywords: colorectal masses; conventional colonoscopy; inflammatory bowel disease; magnetic resonance imaging; virtual colonoscopy

Abbreviations: MR, magnetic resonance; MRC, MR colonography; CT, computed tomography; ROI, regions of interest; CNR, contrast to noise ratios

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