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Review
Gene therapy of hepatic diseases: prospects for the new millennium

https://doi.org/10.1136/gut.46.1.136

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    Footnotes

    • *Note added in proof: A troubling development has occurred in a clinical trial of adenoviral gene therapy for ornithine transcarbamylase deficiency. The unexplained death of one of the trial patients has resulted in the indefinite suspension of the trial.

    • Abbreviations used in this review:
      AAV
      adeno-associated virus
      AsGPr
      asialoglycoprotein receptor
      BUGT
      bilirubin-UDP- glucuronyltransferase
      GSD
      glycogen storage disease
      HCV
      hepatitis C virus
      HSV-tk
      herpes simplex virus thymidine kinase
      hGAA
      human acid α-glucosidase
      IL
      interleukin
      LDL
      low density lipoprotein
      OTC
      ornithine transcarbamylase
      SV-40
      Simian virus 40