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Recent advances in basic science
Apoptosis and colorectal cancer

https://doi.org/10.1136/gut.2004.052704

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    Footnotes

    • ↵* If we assume there are 30 000 human genes, each of which can exist in at least two forms, then there are a minimum of 230 000 or 109031 possible combinations of genes. This illustrates that the number of genetic changes potentially related to malignant transformation is hugely greater that the minimum number of phenotypic changes required.