Article Text

Download PDFPDF
Novel targets for the control of secretory diarrhoea
  1. M J G Farthing
  1. Correspondence to:
    Prof. M J G Farthing, Faculty of Medicine, University of Glasgow, 12 Southpark Terrace, Glasgow G12 8LG, UK;
    m.farthing{at}clinmed.gla.ac.uk

Abstract

Secretory diarrhoea continues to be a major clinical problem worldwide. It is now recognised that the enteric nervous system plays an important role in the pathogenesis of enterotoxin mediated intestinal secretion, which has resulted in the identification of novel therapeutic targets for the treatment of acute watery diarrhoea.

  • intestinal secretion
  • enteric nervous system
  • enterotoxin
  • 5-hydroxytryptamine
  • enkephalinase inhibitor
  • CT, cholera toxin
  • ENS, enteric nervous system
  • LT, heat labile toxin
  • ST, heat stable toxin
  • VIP, vasoactive intestinal peptide

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.