Article Text
Generic methodological issues
A systematic review of symptomatic outcomes used in oesophagitis drug therapy trials
Abstract
Symptoms are an important outcome for measurement in clinical trials into gastro-oesophageal reflux disease, but the optimal approach to symptom assessment has not been formally evaluated. The authors conducted a systematic review to assess how reflux symptoms have been evaluated and how well these correlate with oesophagitis healing and relapse.
- gastro-oesophageal reflux disease
- healing of oesophagitis
- heartburn
- symptom frequency
- symptom severity
- GORD, gastro-oesophageal reflux disease
- PGWBI, psychological general well being index
- SF-36, short form 36
Statistics from Altmetric.com
Linked Articles
- Overview and workshop discussion outputs
- Generic methodological issues
- Generic methodological issues