Table 1 Characteristics of the study groups
Crohn’s diseaseControls
Patient data
No. of subjects6511
Mean age (years)31.4 (SD 11.4)52.7 (SD 17.7)
Sex, female, n35 (54%)8 (73%)
Ileal involvement, n65 (100%)
Medical treatment
    None, n37 (57%)
    Treatment, n28 (43%)
        Monotherapy, n13
            Immunosuppression, n10
            Steroids, n2
            5-ASA, n1
        Combination therapy, n15
Sample data
No. of samples9511
Type
    Resection, n21 (22%)0 (0%)
    Biopsy, n74 (78%)11 (100%)
Histology
    Non-inflamed, n51 (54%)11 (100%)
    Inflamed, n44 (46%)0 (0%)
NOD2 status
    Wild-type, n58 (61%)8 (73%)
    Mutant*, n37 (39%)3 (27%)
  • *Heterozygous or homozygous for any variant (R702W, G908R, 1007fs).