cell death

Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade
Claire Conche, Fabian Finkelmeier, Marina Pešić, Adele M Nicolas, Tim W Böttger, Kilian B Kennel, Dominic Denk, Fatih Ceteci, Kathleen Mohs, Esther Engel, Özge Canli, Yasamin Dabiri, Kai-Henrik Peiffer, Stefan Zeuzem, Gabriela Salinas, Thomas Longerich, Huan Yang, Florian R Greten

Gut Sep 2023, 72 (9) 1774-1782; DOI: 10.1136/gutjnl-2022-327909
Preclinical mouse model of a misfolded PNLIP variant develops chronic pancreatitis
Guoying Zhu, Steven J Wilhelm, Leah G George, Brett M Cassidy, Sammy Zino, Cliff J Luke, Mina Hanna, Stephen Stone, Nhung Phan, Neel Matiwala, Samuel J Ballentine, Mark E Lowe, Xunjun Xiao

Gut Jul 2023, 72 (7) 1340-1354; DOI: 10.1136/gutjnl-2022-327960
Reticulon 3-mediated Chk2/p53 activation suppresses hepatocellular carcinogenesis and is blocked by hepatitis B virus
Shushu Song, Yinghong Shi, Weicheng Wu, Hao Wu, Lei Chang, Peike Peng, Lei Zhang, Jia Fan, Jianxin Gu, Yuanyuan Ruan

Gut Nov 2021, 70 (11) 2159-2171; DOI: 10.1136/gutjnl-2020-321386
CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer
Jin Huang, Pan Chen, Ke Liu, Jiao Liu, Borong Zhou, Runliu Wu, Qiu Peng, Ze-Xian Liu, Changfeng Li, Guido Kroemer, Michael Lotze, Herbert Zeh, Rui Kang, Daolin Tang

Gut May 2021, 70 (5) 890-899; DOI: 10.1136/gutjnl-2019-320441
RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease
Marta B Afonso, Pedro M Rodrigues, Miguel Mateus-Pinheiro, André L Simão, Maria M Gaspar, Amine Majdi, Enara Arretxe, Cristina Alonso, Alvaro Santos-Laso, Raul Jimenez-Agüero, Emma Eizaguirre, Luis Bujanda, Maria Jesus Pareja, Jesus M Banales, Vlad Ratziu, Jeremie Gautheron, Rui E Castro, Cecília M P Rodrigues

Gut Dec 2021, 70 (12) 2359-2372; DOI: 10.1136/gutjnl-2020-321767
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP
Rajarshi Mukherjee, Olga A Mareninova, Irina V Odinokova, Wei Huang, John Murphy, Michael Chvanov, Muhammad A Javed, Li Wen, David M Booth, Matthew C Cane, Muhammad Awais, Bruno Gavillet, Rebecca M Pruss, Sophie Schaller, Jeffery D Molkentin, Alexei V Tepikin, Ole H Petersen, Stephen J Pandol, Ilya Gukovsky, David N Criddle, Anna S Gukovskaya, Robert Sutton

Gut Aug 2016, 65 (8) 1333-1346; DOI: 10.1136/gutjnl-2014-308553
Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium
Claudia Günther, Helmut Neumann, Markus F Neurath, Christoph Becker

Gut Jul 2013, 62 (7) 1062-1071; DOI: 10.1136/gutjnl-2011-301364
Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression
Mi Jeong Heo, Tae Hyun Kim, Jueng Soo You, Delia Blaya, Pau Sancho-Bru, Sang Geon Kim

Gut Apr 2019, 68 (4) 708-720; DOI: 10.1136/gutjnl-2017-315123
PGAM5: a new player in immune-mediated liver injury
Anup Ramachandran, Hartmut Jaeschke

Gut Apr 2017, 66 (4) 567-568; DOI: 10.1136/gutjnl-2016-312775
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
Michael A Jacobetz, Derek S Chan, Albrecht Neesse, Tashinga E Bapiro, Natalie Cook, Kristopher K Frese, Christine Feig, Tomoaki Nakagawa, Meredith E Caldwell, Heather I Zecchini, Martijn P Lolkema, Ping Jiang, Anne Kultti, Curtis B Thompson, Daniel C Maneval, Duncan I Jodrell, Gregory I Frost, H M Shepard, Jeremy N Skepper, David A Tuveson

Gut Jan 2013, 62 (1) 112-120; DOI: 10.1136/gutjnl-2012-302529

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