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colon carcinogenesis

  • Targeting m6A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer
    Yi Bao, Jianning Zhai, Huarong Chen, Chi Chun Wong, Cong Liang, Yanqiang Ding, Dan Huang, Hongyan Gou, Danyu Chen, Yasi Pan, Wei Kang, Ka Fai To, Jun Yu
    Gut Aug 2023, 72 (8) 1497-1509; DOI: 10.1136/gutjnl-2022-328845
  • Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer
    Elias Orouji, Ayush T Raman, Anand K Singh, Alexey Sorokin, Emre Arslan, Archit K Ghosh, Jonathan Schulz, Christopher Terranova, Shan Jiang, Ming Tang, Mayinuer Maitituoheti, Scot C Callahan, Praveen Barrodia, Katarzyna Tomczak, Yingda Jiang, Zhiqin Jiang, Jennifer S Davis, Sukhen Ghosh, Hey Min Lee, Laura Reyes-Uribe, Kyle Chang, Yusha Liu, Huiqin Chen, Ali Azhdarinia, Jeffrey Morris, Eduardo Vilar, Kendra S Carmon, Scott E Kopetz, Kunal Rai
    Gut May 2022, 71 (5) 938-949; DOI: 10.1136/gutjnl-2020-322835
  • Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer
    Shania M Corry, Amy MB McCorry, Tamsin RM Lannagan, Niamh A Leonard, Natalie C Fisher, Ryan M Byrne, Petros Tsantoulis, Xabier Cortes-Lavaud, Raheleh Amirkhah, Keara L Redmond, Aoife J McCooey, Sudhir B Malla, Emily Rogan, Svetlana Sakhnevych, Michael A Gillespie, Mark White, Susan D Richman, Rene-Filip Jackstadt, Andrew D Campbell, Sarah Maguire, S:CORT and ACRCelerate consortia, Simon S McDade, Daniel B Longley, Maurice B Loughrey, Helen G Coleman, Emma M Kerr, Sabine Tejpar, Timothy Maughan, Simon J Leedham, Donna M Small, Aideen E Ryan, Owen J Sansom, Mark Lawler, Philip D Dunne
    Gut Dec 2022, 71 (12) 2502-2517; DOI: 10.1136/gutjnl-2021-326183
  • RNA binding protein DDX5 directs tuft cell specification and function to regulate microbial repertoire and disease susceptibility in the intestine
    Tianyun Long, Nazia Abbasi, Juan E Hernandez, Yuxin Li, Ibrahim M Sayed, Shengyun Ma, Attilio Iemolo, Brian A Yee, Gene W Yeo, Francesca Telese, Pradipta Ghosh, Soumita Das, Wendy Jia Men Huang
    Gut Sep 2022, 71 (9) 1790-1802; DOI: 10.1136/gutjnl-2021-324984
  • Only fibres promoting a stable butyrate producing colonic ecosystem decrease the rate of aberrant crypt foci in rats
    P Perrin, F Pierre, Y Patry, M Champ, M Berreur, G Pradal, F Bornet, K Meflah, J Menanteau
    Gut Jan 2001, 48 (1) 53-61; DOI: 10.1136/gut.48.1.53
  • Genetic architectures of proximal and distal colorectal cancer are partly distinct
    Jeroen R Huyghe, Tabitha A Harrison, Stephanie A Bien, Heather Hampel, Jane C Figueiredo, Stephanie L Schmit, David V Conti, Sai Chen, Conghui Qu, Yi Lin, Richard Barfield, John A Baron, Amanda J Cross, Brenda Diergaarde, David Duggan, Sophia Harlid, Liher Imaz, Hyun Min Kang, David M Levine, Vittorio Perduca, Aurora Perez-Cornago, Lori C Sakoda, Fredrick R Schumacher, Martha L Slattery, Amanda E Toland, Fränzel J B van Duijnhoven, Bethany Van Guelpen, Antonio Agudo, Demetrius Albanes, M Henar Alonso, Kristin Anderson, Coral Arnau-Collell, Volker Arndt, Barbara L Banbury, Michael C Bassik, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, Juergen Boehm, Heiner Boeing, Marie-Christine Boutron-Ruault, Hermann Brenner, Stefanie Brezina, Stephan Buch, Daniel D Buchanan, Andrea Burnett-Hartman, Bette J Caan, Peter T Campbell, Prudence R Carr, Antoni Castells, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Keith R Curtis, Albert de la Chapelle, Douglas F Easton, Dallas R English, Edith J M Feskens, Manish Gala, Steven J Gallinger, W James Gauderman, Graham G Giles, Phyllis J Goodman, William M Grady, John S Grove, Andrea Gsur, Marc J Gunter, Robert W Haile, Jochen Hampe, Michael Hoffmeister, John L Hopper, Wan-Ling Hsu, Wen-Yi Huang, Thomas J Hudson, Mazda Jenab, Mark A Jenkins, Amit D Joshi, Temitope O Keku, Charles Kooperberg, Tilman Kühn, Sébastien Küry, Loic Le Marchand, Flavio Lejbkowicz, Christopher I Li, Li Li, Wolfgang Lieb, Annika Lindblom, Noralane M Lindor, Satu Männistö, Sanford D Markowitz, Roger L Milne, Lorena Moreno, Neil Murphy, Rami Nassir, Kenneth Offit, Shuji Ogino, Salvatore Panico, Patrick S Parfrey, Rachel Pearlman, Paul D P Pharoah, Amanda I Phipps, Elizabeth A Platz, John D Potter, Ross L Prentice, Lihong Qi, Leon Raskin, Gad Rennert, Hedy S Rennert, Elio Riboli, Clemens Schafmayer, Robert E Schoen, Daniela Seminara, Mingyang Song, Yu-Ru Su, Catherine M Tangen, Stephen N Thibodeau, Duncan C Thomas, Antonia Trichopoulou, Cornelia M Ulrich, Kala Visvanathan, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Korbinian Weigl, Stephanie J Weinstein, Emily White, Alicja Wolk, Michael O Woods, Anna H Wu, Goncalo R Abecasis, Deborah A Nickerson, Peter C Scacheri, Anshul Kundaje, Graham Casey, Stephen B Gruber, Li Hsu, Victor Moreno, Richard B Hayes, Polly A Newcomb, Ulrike Peters
    Gut Jul 2021, 70 (7) 1325-1334; DOI: 10.1136/gutjnl-2020-321534
  • Calcium and vitamin D supplementation and increased risk of serrated polyps: results from a randomised clinical trial
    Seth D Crockett, Elizabeth L Barry, Leila A Mott, Dennis J Ahnen, Douglas J Robertson, Joseph C Anderson, Kristen Wallace, Carol A Burke, Robert S Bresalier, Jane C Figueiredo, Dale C Snover, John A Baron
    Gut Mar 2019, 68 (3) 475-486; DOI: 10.1136/gutjnl-2017-315242
  • Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles
    Helen H N Yan, Hoi Cheong Siu, Siu Lun Ho, Sarah S K Yue, Yang Gao, Wai Yin Tsui, Dessy Chan, April S Chan, Jason W H Wong, Alice H Y Man, Bernard C H Lee, Annie S Y Chan, Anthony K W Chan, Ho Sang Hui, Arthur K L Cheung, Wai Lun Law, Oswens S H Lo, Siu Tsan Yuen, Hans Clevers, Suet Yi Leung
    Gut Dec 2020, 69 (12) 2165-2179; DOI: 10.1136/gutjnl-2019-320019
  • Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma
    Paolo Carrega, Paola Orecchia, Linda Quatrini, Nicola Tumino, Roberta Venè, Roberto Benelli, Alessandro Poggi, Stefano Scabini, Maria Cristina Mingari, Lorenzo Moretta, Paola Vacca
    Gut Dec 2020, 69 (12) 2261-2263; DOI: 10.1136/gutjnl-2020-320908
  • Genomic and transcriptomic profiling of carcinogenesis in patients with familial adenomatous polyposis
    Jingyun Li, Rui Wang, Xin Zhou, Wendong Wang, Shuai Gao, Yunuo Mao, Xinglong Wu, Limei Guo, Haijing Liu, Lu Wen, Wei Fu, Fuchou Tang
    Gut Jul 2020, 69 (7) 1283-1293; DOI: 10.1136/gutjnl-2019-319438

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