immunology in hepatology

Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies
Dorothea Bankwitz, Akash Bahai, Maurice Labuhn, Mandy Doepke, Corinne Ginkel, Tanvi Khera, Daniel Todt, Luisa J Ströh, Leona Dold, Florian Klein, Frank Klawonn, Thomas Krey, Patrick Behrendt, Markus Cornberg, Alice C McHardy, Thomas Pietschmann

Gut Sep 2021, 70 (9) 1734-1745; DOI: 10.1136/gutjnl-2020-321190
Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease
Stephan Urban, Christoph Neumann-Haefelin, Pietro Lampertico

Gut Sep 2021, 70 (9) 1782-1794; DOI: 10.1136/gutjnl-2020-323888
HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells
Britta F Zecher, David Ellinghaus, Sebastian Schloer, Annika Niehrs, Benedetta Padoan, Martin E Baumdick, Yuko Yuki, Maureen P Martin, Dawid Glow, Jennifer Schröder-Schwarz, Jennifer Niersch, Sébastien Brias, Luisa M Müller, Robin Habermann, Paul Kretschmer, Tristan Früh, Janis Dänekas, Malte H Wehmeyer, Tobias Poch, Marcial Sebode, International PSC Study Group (IPSCSG), Eva Ellinghaus, Frauke Degenhardt, Christian Körner, Angelique Hoelzemer, Boris Fehse, Karl J Oldhafer, Udo Schumacher, Guido Sauter, Mary Carrington, Andre Franke, Madeleine J Bunders, Christoph Schramm, Marcus Altfeld

Gut Feb 2024, 73 (2) 325-337; DOI: 10.1136/gutjnl-2023-329524
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8⁺ T cells
Frances Winkler, Anna V Hipp, Carlos Ramirez, Bianca Martin, Matteo Villa, Emilia Neuwirt, Oliver Gorka, Jeroen Aerssens, Susanne E Johansson, Nisha Rana, Sian Llewellyn-Lacey, David A Price, Marcus Panning, Olaf Groß, Erika L Pearce, Carl M Hermann, Kathrin Schumann, Luciana Hannibal, Christoph Neumann-Haefelin, Tobias Boettler, Percy Knolle, Maike Hofmann, Dirk Wohlleber, Robert Thimme, Bertram Bengsch

Gut Oct 2023, 72 (10) 1971-1984; DOI: 10.1136/gutjnl-2022-328734
Suppressor CD4⁺ T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis
Wafa Khamri, Cathrin Gudd, Tong Liu, Rooshi Nathwani, Marigona Krasniqi, Sofia Azam, Thomas Barbera, Francesca M Trovato, Lucia Possamai, Evangelos Triantafyllou, Rocio Castro Seoane, Fanny Lebosse, Arjuna Singanayagam, Naveenta Kumar, Christine Bernsmeier, Sujit Mukherjee, Mark McPhail, Chris J Weston, Charalambos Gustav Antoniades, Mark R Thursz

Gut Jun 2022, 71 (6) 1192-1202; DOI: 10.1136/gutjnl-2021-324071
Immunogenomic classification of hepatocellular carcinoma patients for immune check-point inhibitors therapy: cui bono?
Ruben Hernaez, Matias A Avila

Gut Jan 2023, 72 (1) 7-9; DOI: 10.1136/gutjnl-2022-327132
Prophylactic vaccination against hepatitis D virus superinfection: from fiction to reality?
Julia Lang-Meli, Christoph Neumann-Haefelin

Gut Jun 2023, 72 (6) 1030-1032; DOI: 10.1136/gutjnl-2022-328381
Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis
Eun Hee Koh, Ji Eun Yoon, Myoung Seok Ko, Jaechan Leem, Ji-Young Yun, Chung Hwan Hong, Yun Kyung Cho, Seung Eun Lee, Jung Eun Jang, Ji Yeon Baek, Hyun Ju Yoo, Su Jung Kim, Chang Ohk Sung, Joon Seo Lim, Won-Il Jeong, Sung Hoon Back, In-Jeoung Baek, Sandra Torres, Estel Solsona-Vilarrasa, Laura Conde de la Rosa, Carmen Garcia-Ruiz, Ariel E Feldstein, Jose C Fernandez-Checa, Ki-Up Lee

Gut Oct 2021, 70 (10) 1954-1964; DOI: 10.1136/gutjnl-2020-322509
Poly I:C-based rHBVvac therapeutic vaccine eliminates HBV via generation of HBV-specific CD8⁺ effector memory T cells
Hua-Jun Zhao, Qiu-Ju Han, Guan Wang, Ang Lin, Dong-Qing Xu, Ya-Qun Wang, Lian-Hui Zhao, Zhi-Gang Tian, Jian Zhang

Gut Nov 2019, 68 (11) 2032-2043; DOI: 10.1136/gutjnl-2017-315588
Inhibition of glutamine synthetase in monocytes from patients with acute-on-chronic liver failure resuscitates their antibacterial and inflammatory capacity
Hannelie Korf, Johannie du Plessis, Jos van Pelt, Sofie De Groote, David Cassiman, Len Verbeke, Bart Ghesquière, Sarah-Maria Fendt, Matthew J Bird, Ali Talebi, Matthias Van Haele, Rita Feio-Azevedo, Lore Meelberghs, Tania Roskams, Rajeshwar P Mookerjee, Gautam Mehta, Rajiv Jalan, Thierry Gustot, Wim Laleman, Frederik Nevens, Schalk Willem van der Merwe

Gut Oct 2019, 68 (10) 1872-1883; DOI: 10.1136/gutjnl-2018-316888

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