molecular carcinogenesis

Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
Carolina F Ruivo, Nuno Bastos, Barbara Adem, Ines Batista, Cecilia Duraes, Carlos A Melo, Stephanie A Castaldo, Francisco Campos‐Laborie, Pedro Moutinho-Ribeiro, Barbara Morão, Ana Costa-Pinto, Soraia Silva, Hugo Osorio, Sergio Ciordia, Jose Luis Costa, David Goodrich, Bruno Cavadas, Luisa Pereira, Tony Kouzarides, Guilherme Macedo, Rui Maio, Fatima Carneiro, Marília Cravo, Raghu Kalluri, Jose Carlos Machado, Sonia A Melo

Gut Oct 2022, 71 (10) 2043-2068; DOI: 10.1136/gutjnl-2021-324994
Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer
Steffie Revia, Agnieszka Seretny, Lena Wendler, Ana Banito, Christoph Eckert, Kersten Breuer, Anand Mayakonda, Pavlo Lutsik, Matthias Evert, Silvia Ribback, Suchira Gallage, Ismaiel Chikh Bakri, Kai Breuhahn, Peter Schirmacher, Stefan Heinrich, Matthias M Gaida, Mathias Heikenwälder, Diego F Calvisi, Christoph Plass, Scott W Lowe, Darjus F Tschaharganeh

Gut Aug 2022, 71 (8) 1613-1628; DOI: 10.1136/gutjnl-2021-325405
Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity
Tu-Xiong Huang, Xiang-Yu Tan, Hui-Si Huang, Yu-Ting Li, Bei-Lei Liu, Kai-Sheng Liu, Xinchun Chen, Zhe Chen, Xin-Yuan Guan, Chang Zou, Li Fu

Gut Feb 2022, 71 (2) 333-344; DOI: 10.1136/gutjnl-2020-322924
Pancreatic cancer risk and levels of trace elements
André F S Amaral, Miquel Porta, Debra T Silverman, Roger L Milne, Manolis Kogevinas, Nathaniel Rothman, Kenneth P Cantor, Brian P Jackson, José A Pumarega, Tomàs López, Alfredo Carrato, Luisa Guarner, Francisco X Real, Núria Malats

Gut Nov 2012, 61 (11) 1583-1588; DOI: 10.1136/gutjnl-2011-301086
TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Aitor Esparza-Baquer, Ibone Labiano, Omar Sharif, Aloña Agirre-Lizaso, Fiona Oakley, Pedro M Rodrigues, Ekaterina Zhuravleva, Colm J O'Rourke, Elizabeth Hijona, Raul Jimenez-Agüero, Ioana Riaño, Ana Landa, Adelaida La Casta, Marco Y W Zaki, Patricia Munoz-Garrido, Mikel Azkargorta, Felix Elortza, Andrea Vogel, Gernot Schabbauer, Patricia Aspichueta, Jesper B Andersen, Sylvia Knapp, Derek A Mann, Luis Bujanda, Jesus Maria Banales, Maria Jesus Perugorria

Gut Jul 2021, 70 (7) 1345-1361; DOI: 10.1136/gutjnl-2019-319227
RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease
Marta B Afonso, Pedro M Rodrigues, Miguel Mateus-Pinheiro, André L Simão, Maria M Gaspar, Amine Majdi, Enara Arretxe, Cristina Alonso, Alvaro Santos-Laso, Raul Jimenez-Agüero, Emma Eizaguirre, Luis Bujanda, Maria Jesus Pareja, Jesus M Banales, Vlad Ratziu, Jeremie Gautheron, Rui E Castro, Cecília M P Rodrigues

Gut Dec 2021, 70 (12) 2359-2372; DOI: 10.1136/gutjnl-2020-321767
miR-541 potentiates the response of human hepatocellular carcinoma to sorafenib treatment by inhibiting autophagy
Wen-Ping Xu, Jin-Pei Liu, Ji-Feng Feng, Chang-Peng Zhu, Yuan Yang, Wei-Ping Zhou, Jin Ding, Chen-Kai Huang, Ya-Lu Cui, Chen-Hong Ding, Xin Zhang, Bin Lu, Wei-Fen Xie

Gut Jul 2020, 69 (7) 1309-1321; DOI: 10.1136/gutjnl-2019-318830
Stromal biology and therapy in pancreatic cancer: ready for clinical translation?
Albrecht Neesse, Christian Alexander Bauer, Daniel Öhlund, Matthias Lauth, Malte Buchholz, Patrick Michl, David A Tuveson, Thomas M Gress

Gut Jan 2019, 68 (1) 159-171; DOI: 10.1136/gutjnl-2018-316451
RSPO2 gene rearrangement: a powerful driver of β-catenin activation in liver tumours
Thomas Longerich, Volker Endris, Olaf Neumann, Eugen Rempel, Martina Kirchner, Zahra Abadi, Sebastian Uhrig, Mark Kriegsmann, Karl Heinz Weiss, Kai Breuhahn, Arianeb Mehrabi, Tim Frederik Weber, Ludwig Wilkens, Beate K Straub, Andreas Rosenwald, Falko Schulze, Benedikt Brors, Stefan Froehling, Rossella Pellegrino, Jan Budczies, Peter Schirmacher, Albrecht Stenzinger

Gut Jul 2019, 68 (7) 1287-1296; DOI: 10.1136/gutjnl-2018-317632
SENP1 activity sustains cancer stem cell in hypoxic HCC
Alice Conigliaro, Marco Tripodi, Maurizio Parola

Gut Dec 2017, 66 (12) 2051-2052; DOI: 10.1136/gutjnl-2017-313946

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