Loss of transforming growth factor β signalling in the intestine contributes to tissue injury in inflammatory bowel disease

K-B Hahm; Y-H Im; T W Parks; S-H Park; S Markowitz; H-Y Jung; J Green; S-J Kim

doi:10.1136/gut.49.2.190

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Inflammation and inflammatory bowel disease

Loss of transforming growth factor β signalling in the intestine contributes to tissue injury in inflammatory bowel disease

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	Abstract	Full	Pdf
Jul 2001	94	463	218
Aug 2001	68	455	169
Sep 2001	53	105	55
Oct 2001	28	142	69
Nov 2001	11	91	38
Dec 2001	13	69	20
Jan 2002	4	67	13
Feb 2002	6	38	15
Mar 2002	4	50	25
Apr 2002	6	37	22
May 2002	5	43	19
Jun 2002	1	40	21
Jul 2002	5	23	19
Aug 2002	1	38	23
Sep 2002	6	33	12
Oct 2002	2	38	19
Nov 2002	3	22	13
Dec 2002	3	23	10
Jan 2003	2	31	17
Feb 2003	2	35	15
Mar 2003	1	29	18
Apr 2003	3	40	17
May 2003	6	25	11
Jun 2003	5	25	10
Jul 2003	9	39	19
Aug 2003	12	18	7
Sep 2003	10	32	17
Oct 2003	15	28	13
Nov 2003	17	30	13
Dec 2003	15	30	11
Jan 2004	16	18	11
Feb 2004	17	29	11
Mar 2004	17	34	20
Apr 2004	18	28	14
May 2004	33	62	16
Jun 2004	44	94	26
Jul 2004	50	96	29
Aug 2004	31	67	30
Sep 2004	34	72	27
Oct 2004	12	51	31
Nov 2004	7	42	33
Dec 2004	15	66	30
Jan 2005	10	62	31
Feb 2005	12	44	14
Mar 2005	13	49	28
Apr 2005	6	22	18
May 2005	6	25	18
Jun 2005	8	37	34
Jul 2005	7	26	23
Aug 2005	6	24	20
Sep 2005	7	30	13
Oct 2005	5	33	13
Nov 2005	5	43	36
Dec 2005	15	46	28
Jan 2006	9	40	27
Feb 2006	10	36	19
Mar 2006	4	42	25
Apr 2006	2	34	17
May 2006	11	24	12
Jun 2006	5	36	26
Jul 2006	4	23	21
Aug 2006	4	35	15
Sep 2006	4	27	21
Oct 2006	12	24	21
Nov 2006	7	30	13
Dec 2006	5	27	14
Jan 2007	9	30	29
Feb 2007	6	26	17
Mar 2007	7	24	24
Apr 2007	14	18	15
May 2007	14	7	8
Jun 2007	16	6	8
Jul 2007	9	16	8
Aug 2007	4	7	9
Sep 2007	15	11	5
Oct 2007	7	10	13
Nov 2007	7	4	1
Dec 2007	6	11	15
Jan 2008	7	9	8
Feb 2008	10	11	10
Mar 2008	30	5	5
Apr 2008	18	6	10
May 2008	15	12	11
Jun 2008	9	12	11
Jul 2008	28	9	7
Aug 2008	28	6	4
Sep 2008	29	8	13
Oct 2008	29	9	7
Nov 2008	12	3	5
Dec 2008	17	8	9
Jan 2009	19	1	2
Feb 2009	10	6	3
Mar 2009	21	13	17
Apr 2009	11	8	6
May 2009	11	4	4
Jun 2009	8	5	7
Jul 2009	9	4	5
Aug 2009	8	4	6
Sep 2009	8	14	12
Oct 2009	25	9	6
Nov 2009	44	17	13
Dec 2009	6	5	3
Jan 2010	12	4	8
Feb 2010	8	5	6
Mar 2010	11	8	6
Apr 2010	8	13	10
May 2010	10	10	8
Jun 2010	7	7	7
Jul 2010	8	3	7
Aug 2010	4	5	3
Sep 2010	3	0	1
Oct 2010	7	4	2
Nov 2010	16	6	3
Dec 2010	8	5	0
Jan 2011	8	12	9
Feb 2011	12	21	4
Mar 2011	12	12	5
Apr 2011	13	2	3
May 2011	20	5	5
Jun 2011	18	9	11
Jul 2011	16	1	1
Aug 2011	7	13	7
Sep 2011	19	6	4
Oct 2011	24	8	4
Nov 2011	21	22	8
Dec 2011	20	43	9
Jan 2012	12	22	4
Feb 2012	7	17	9
Mar 2012	13	27	11
Apr 2012	9	8	2
May 2012	13	10	9
Jun 2012	21	18	15
Jul 2012	16	28	15
Aug 2012	7	14	10
Sep 2012	7	11	19
Oct 2012	9	23	6
Nov 2012	6	17	7
Dec 2012	15	9	22
Jan 2013	9	6	5
Feb 2013	15	24	14
Mar 2013	10	16	7
Apr 2013	19	12	9
May 2013	16	10	21
Jun 2013	8	8	15
Jul 2013	11	9	3
Aug 2013	18	10	15
Sep 2013	14	15	5
Oct 2013	20	17	8
Nov 2013	12	12	28
Dec 2013	14	19	4
Jan 2014	19	11	8
Feb 2014	4	11	22
Mar 2014	10	22	37
Apr 2014	13	15	20
May 2014	21	7	22
Jun 2014	15	8	9
Jul 2014	29	13	3
Aug 2014	8	8	9
Sep 2014	12	4	3
Oct 2014	10	15	8
Nov 2014	18	13	7
Dec 2014	10	9	2
Jan 2015	18	15	7
Feb 2015	2	14	10
Mar 2015	5	17	10
Apr 2015	5	12	6
May 2015	15	30	6
Jun 2015	12	18	7
Jul 2015	11	21	7
Aug 2015	7	12	3
Sep 2015	20	14	3
Oct 2015	7	7	0
Nov 2015	7	10	3
Dec 2015	10	8	4
Jan 2016	14	22	6
Feb 2016	7	9	8
Mar 2016	17	6	10
Apr 2016	39	13	3
May 2016	10	20	4
Jun 2016	7	7	8
Jul 2016	20	9	6
Aug 2016	13	9	7
Sep 2016	20	14	6
Oct 2016	27	5	3
Nov 2016	25	6	3
Dec 2016	16	19	2
Jan 2017	17	15	5
Feb 2017	10	3	1
Mar 2017	4	22	3
Apr 2017	1	20	2
May 2017	1	32	7
Jun 2017	3	13	6
Jul 2017	10	8	6
Aug 2017	30	26	6
Sep 2017	11	11	1
Oct 2017	25	23	6
Nov 2017	17	17	11
Dec 2017	18	16	5
Jan 2018	32	32	6
Feb 2018	25	17	3
Mar 2018	40	38	2
Apr 2018	24	27	4
May 2018	16	15	4
Jun 2018	28	28	6
Jul 2018	20	20	8
Aug 2018	24	24	4
Sep 2018	8	8	6
Oct 2018	23	23	12
Nov 2018	23	24	4
Dec 2018	25	25	10
Jan 2019	14	14	10
Feb 2019	23	15	11
Mar 2019	39	36	15
Apr 2019	26	20	15
May 2019	47	36	24
Jun 2019	32	28	19
Jul 2019	42	43	16
Aug 2019	28	26	17
Sep 2019	31	26	16
Oct 2019	57	55	25
Nov 2019	42	43	17
Dec 2019	64	62	15
Jan 2020	46	38	10
Feb 2020	36	27	11
Mar 2020	38	38	13
Apr 2020	20	18	16
May 2020	33	29	12
Jun 2020	31	29	11
Jul 2020	27	28	7
Aug 2020	21	19	9
Sep 2020	35	32	5
Oct 2020	51	49	13
Nov 2020	32	30	13
Dec 2020	41	37	12
Jan 2021	48	44	21
Feb 2021	28	26	8
Mar 2021	34	26	13
Apr 2021	16	16	10
May 2021	46	43	23
Jun 2021	42	41	16
Jul 2021	16	16	7
Aug 2021	20	20	10
Sep 2021	38	38	13
Oct 2021	46	40	33
Nov 2021	36	30	22
Dec 2021	17	18	11
Jan 2022	26	25	7
Feb 2022	51	42	21
Mar 2022	30	30	25
Apr 2022	66	50	13
May 2022	46	38	30
Jun 2022	56	49	15
Jul 2022	32	25	8
Aug 2022	49	43	6
Sep 2022	43	41	19
Oct 2022	51	46	15
Nov 2022	45	38	12
Dec 2022	50	46	17
Jan 2023	52	39	17
Feb 2023	83	73	9
Mar 2023	47	39	17
Apr 2023	58	46	21
May 2023	33	26	12
Jun 2023	30	27	11
Jul 2023	28	25	10
Aug 2023	38	34	9
Sep 2023	49	39	23
Oct 2023	44	29	9
Nov 2023	84	57	10
Dec 2023	204	15	4
Jan 2024	103	4	2
Feb 2024	126	3	2
Mar 2024	70	2	1
Total	5775	7568	3737

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