Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy

Suzanne Hector; Markus Rehm; Jasmin Schmid; Joan Kehoe; Niamh McCawley; Patrick Dicker; Frank Murray; Deborah McNamara; Elaine W Kay; Caoimhin G Concannon; Heinrich J Huber; Jochen H M Prehn

doi:10.1136/gutjnl-2011-300433

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Original article

Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy

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Nov 2011	152	76	67
Dec 2011	73	45	34
Jan 2012	107	52	18
Feb 2012	81	29	15
Mar 2012	94	39	14
Apr 2012	818	17	70
May 2012	444	25	40
Jun 2012	225	22	18
Jul 2012	188	8	11
Aug 2012	99	9	8
Sep 2012	118	18	23
Oct 2012	111	38	20
Nov 2012	90	44	38
Dec 2012	71	8	11
Jan 2013	92	17	25
Feb 2013	62	18	13
Mar 2013	57	12	11
Apr 2013	107	14	11
May 2013	53	4	8
Jun 2013	37	7	5
Jul 2013	43	9	7
Aug 2013	51	8	10
Sep 2013	35	8	4
Oct 2013	38	23	12
Nov 2013	35	18	10
Dec 2013	34	6	7
Jan 2014	34	14	9
Feb 2014	23	6	4
Mar 2014	36	15	1
Apr 2014	38	8	9
May 2014	33	8	12
Jun 2014	19	8	9
Jul 2014	53	12	11
Aug 2014	23	10	6
Sep 2014	48	6	2
Oct 2014	38	7	8
Nov 2014	31	10	3
Dec 2014	32	5	3
Jan 2015	17	5	4
Feb 2015	17	5	4
Mar 2015	36	11	8
Apr 2015	17	11	7
May 2015	26	6	5
Jun 2015	17	6	12
Jul 2015	16	12	5
Aug 2015	25	22	4
Sep 2015	34	12	8
Oct 2015	17	5	5
Nov 2015	13	4	1
Dec 2015	26	7	5
Jan 2016	22	6	5
Feb 2016	22	0	1
Mar 2016	22	5	5
Apr 2016	22	3	3
May 2016	12	11	5
Jun 2016	33	1	1
Jul 2016	39	1	1
Aug 2016	33	2	0
Sep 2016	24	1	1
Oct 2016	33	12	6
Nov 2016	16	4	1
Dec 2016	22	4	2
Jan 2017	29	4	4
Feb 2017	29	3	1
Mar 2017	31	7	6
Apr 2017	22	4	5
May 2017	29	10	3
Jun 2017	20	7	5
Jul 2017	41	2	2
Aug 2017	99	3	1
Sep 2017	58	7	2
Oct 2017	62	3	2
Nov 2017	70	1	0
Dec 2017	59	0	0
Jan 2018	165	5	4
Feb 2018	72	6	3
Mar 2018	113	4	1
Apr 2018	85	7	1
May 2018	85	4	1
Jun 2018	61	2	1
Jul 2018	42	2	0
Aug 2018	47	9	2
Sep 2018	36	4	2
Oct 2018	88	2	5
Nov 2018	91	0	0
Dec 2018	52	1	1
Jan 2019	43	0	2
Feb 2019	61	6	4
Mar 2019	66	6	1
Apr 2019	54	2	0
May 2019	66	4	2
Jun 2019	50	2	2
Jul 2019	32	2	2
Aug 2019	49	7	4
Sep 2019	50	4	1
Oct 2019	35	2	2
Nov 2019	45	5	4
Dec 2019	54	4	3
Jan 2020	45	8	2
Feb 2020	53	1	1
Mar 2020	30	0	0
Apr 2020	18	2	1
May 2020	19	3	0
Jun 2020	38	2	1
Jul 2020	36	0	1
Aug 2020	18	0	0
Sep 2020	46	1	0
Oct 2020	45	2	1
Nov 2020	59	0	1
Dec 2020	35	1	1
Jan 2021	46	2	0
Feb 2021	108	4	2
Mar 2021	46	6	0
Apr 2021	60	0	0
May 2021	22	5	7
Jun 2021	2	2	1
Jul 2021	1	1	0
Aug 2021	1	1	1
Sep 2021	3	2	3
Oct 2021	32	2	1
Nov 2021	81	1	0
Dec 2021	25	1	1
Jan 2022	50	3	0
Feb 2022	66	2	2
Mar 2022	52	2	1
Apr 2022	73	5	3
May 2022	71	1	1
Jun 2022	61	3	1
Jul 2022	32	2	1
Aug 2022	56	2	1
Sep 2022	54	4	1
Oct 2022	58	2	0
Nov 2022	55	1	0
Dec 2022	59	1	0
Jan 2023	27	0	0
Feb 2023	13	3	0
Mar 2023	32	8	3
Apr 2023	24	4	0
May 2023	14	2	1
Jun 2023	15	1	0
Jul 2023	41	3	0
Aug 2023	38	2	1
Sep 2023	41	1	0
Oct 2023	26	4	1
Nov 2023	33	2	0
Dec 2023	68	2	1
Jan 2024	40	1	1
Feb 2024	28	0	0
Mar 2024	39	2	2
Total	8410	1090	811

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