Table of contents

Original articles

Oesophagus

• Original article: Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis (17 November, 2012)

  Joanne C Masterson, Eóin N McNamee, Lindsay Hosford, Kelley E Capocelli, Joseph Ruybal, Sophie A Fillon, Alfred D Doyle, Holger K Eltzschig, Anil K Rustgi, Cheryl A Protheroe, Nancy A Lee, James J Lee, Glenn T Furuta

Stomach

• Original article:

  Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis

  (28 June, 2013)

  Kvin Lertpiriyapong, Mark T Whary, Sureshkumar Muthupalani, Jennifer L Lofgren, Eric R Gamazon, Yan Feng, Zhongming Ge, Timothy C Wang, James G Fox
• Original article: The burden of stomach cancer in indigenous populations: a systematic review and global assessment (23 October, 2013)

  Melina Arnold, Suzanne P Moore, Sven Hassler, Lis Ellison-Loschmann, David Forman, Freddie Bray

Inflammatory bowel disease

• Original article: Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study (7 November, 2012)

  Mirthe Emilie van der Valk, Marie-Josée J Mangen, Max Leenders, Gerard Dijkstra, Ad A van Bodegraven, Herma H Fidder, Dirk J de Jong, Marieke Pierik, C Janneke van der Woude, Mariëlle J L Romberg-Camps, Cees HM Clemens, Jeroen M Jansen, Nofel Mahmmod, Paul C van de Meeberg, Andrea E van der Meulen-de Jong, Cyriel Y Ponsioen, Clemens JM Bolwerk, J Reinoud Vermeijden, Peter D Siersema, Martijn GH van Oijen, Bas Oldenburg, on behalf of the COIN study group and the Dutch Initiative on Crohn and Colitis
• Original article: Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations (14 July, 2013)

  Suk-Kyun Yang, Myunghee Hong, Wanting Zhao, Yusun Jung, Jiwon Baek, Naeimeh Tayebi, Kyung Mo Kim, Byong Duk Ye, Kyung-Jo Kim, Sang Hyoung Park, Inchul Lee, Eun-Ju Lee, Won Ho Kim, Jae Hee Cheon, Young-Ho Kim, Byung Ik Jang, Hyun-Soo Kim, Jai Hyun Choi, Ja Seol Koo, Ji Hyun Lee, Sung-Ae Jung, Yeoun Joo Lee, Joo Young Jang, Hyoung Doo Shin, Daehee Kang, Hee-Shang Youn, Jianjun Liu, Kyuyoung Song
• Original article: Clinical disease activity, C-reactive protein normalisation and mucosal healing in Crohn's disease in the SONIC trial (23 August, 2013)

  Laurent Peyrin-Biroulet, Walter Reinisch, Jean-Frederic Colombel, Gerassimos J Mantzaris, Asher Kornbluth, Robert Diamond, Paul Rutgeerts, Linda K Tang, Freddy J Cornillie, William J Sandborn

Intestinal inflammation

• Original article: Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α (25 December, 2012)

  Matthew A Brooke, Hilary J Longhurst, Vincent Plagnol, Nicholas S Kirkby, Jane A Mitchell, Franz Rüschendorf, Timothy D Warner, David P Kelsell, Thomas T MacDonald

Neurogastroenterology

• Original article: Enteroglial-derived S100B protein integrates bacteria-induced Toll-like receptor signalling in human enteric glial cells (3 January, 2013)

  Fabio Turco, Giovanni Sarnelli, Carla Cirillo, Ilaria Palumbo, Francesco De Giorgi, Alessandra D'Alessandro, Marcella Cammarota, Mariateresa Giuliano, Rosario Cuomo

Gut microbiota

• Original article:

  Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation

  (18 April, 2013)

  Margarita Martinez-Medina, Jérémy Denizot, Nicolas Dreux, Frédéric Robin, Elisabeth Billard, Richard Bonnet, Arlette Darfeuille-Michaud, Nicolas Barnich

Endoscopy

• Original article: Telephone-based re-education on the day before colonoscopy improves the quality of bowel preparation and the polyp detection rate: a prospective, colonoscopist-blinded, randomised, controlled study (16 March, 2013)

  Xiaodong Liu, Hui Luo, Lin Zhang, Felix W Leung, Zhiguo Liu, Xiangping Wang, Rui Huang, Na Hui, Kaichun Wu, Daiming Fan, Yanglin Pan, Xuegang Guo

Colon

• Original article: Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells) (24 January, 2013)

  Manoj Puthia, Petter Storm, Aftab Nadeem, Sabrina Hsiung, Catharina Svanborg

Tumour biomarkers

• Original article: A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk (7 January, 2013)

  Meian He, Chen Wu, Jianfeng Xu, Huan Guo, Handong Yang, Xiaomin Zhang, Jielin Sun, Dianke Yu, Li Zhou, Tao Peng, Yunfeng He, Yong Gao, Jing Yuan, Qifei Deng, Xiayun Dai, Aihua Tan, Yingying Feng, Haiying Zhang, Xinwen Min, Xiaobo Yang, Jiang Zhu, Kan Zhai, Jiang Chang, Xue Qin, Wen Tan, Yanling Hu, Mingjian Lang, Sha Tao, Yuanfeng Li, Yi Li, Junjie Feng, Dongfeng Li, Seong-Tae Kim, Shijun Zhang, Hongxing Zhang, S Lilly Zheng, Lixuan Gui, Youjie Wang, Sheng Wei, Feng Wang, Weimin Fang, Yuan Liang, Yun Zhai, Weihong Chen, Xiaoping Miao, Gangqiao Zhou, Frank B Hu, Dongxin Lin, Zengnan Mo, Tangchun Wu

Pancreas

• Original article: Genome-wide association study of survival in patients with pancreatic adenocarcinoma (24 November, 2012)

  Chen Wu, Peter Kraft, Rachael Stolzenberg-Solomon, Emily Steplowski, Michelle Brotzman, Mousheng Xu, Poorva Mudgal, Laufey Amundadottir, Alan A Arslan, H Bas Bueno-de-Mesquita, Myron Gross, Kathy Helzlsouer, Eric J Jacobs, Charles Kooperberg, Gloria M Petersen, Wei Zheng, Demetrius Albanes, Marie-Christine Boutron-Ruault, Julie E Buring, Federico Canzian, Guangwen Cao, Eric J Duell, Joanne W Elena, J Michael Gaziano, Edward L Giovannucci, Goran Hallmans, Amy Hutchinson, David J Hunter, Mazda Jenab, Guoliang Jiang, Kay-Tee Khaw, Andrea LaCroix, Zhaoshen Li, Julie B Mendelsohn, Salvatore Panico, Alpa V Patel, Zhi Rong Qian, Elio Riboli, Howard Sesso, Hongbing Shen, Xiao-Ou Shu, Anne Tjonneland, Geoffrey S Tobias, Dimitrios Trichopoulos, Jarmo Virtamo, Kala Visvanathan, Jean Wactawski-Wende, Chengfeng Wang, Kai Yu, Anne Zeleniuch-Jacquotte, Stephen Chanock, Robert Hoover, Patricia Hartge, Charles S Fuchs, Dongxin Lin, Brian M Wolpin

Hepatology

• Original article: Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C (8 February, 2013)

  Yaron Rotman, Mazen Noureddin, Jordan J Feld, Jeremie Guedj, Michael Witthaus, Hwalih Han, Yoon J Park, Su-Hyung Park, Theo Heller, Marc G Ghany, Edward Doo, Christopher Koh, Adil Abdalla, Naveen Gara, Souvik Sarkar, Emmanuel Thomas, Golo Ahlenstiel, Birgit Edlich, Rachel Titerence, Leah Hogdal, Barbara Rehermann, Harel Dahari, Alan S Perelson, Jay H Hoofnagle, T Jake Liang
• Original article: Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice (24 January, 2013)

  Yan Lu, Zhimin Ma, Zhijian Zhang, Xuelian Xiong, Xiaolin Wang, Huijie Zhang, Guojun Shi, Xuefeng Xia, Guang Ning, Xiaoying Li