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Table of contents

October 2002 - Volume 51 - 4

Leading article

Hepatocellular carcinoma: is current therapy really altering outcome? (1 October, 2002)
P J Johnson

Digest (1 October, 2002)
Ian Forgacs

Commentaries

FAP: another indication to treat H pylori
(1 October, 2002)
B Leggett
Functional dyspepsia: bye-bye to PPIs (1 October, 2002)
O Nyrén

Clinical @lert

Do those with positive faecal occult blood tests need upper gastrointestinal investigations if no colorectal cancer cause is found? (1 October, 2002)
M H Robinson

Debate

Laparoscopic fundoplication is the treatment of choice for gastro-oesophageal reflux disease (1 October, 2002)
L Lundell
Laparoscopic fundoplication is the treatment of choice for gastro-oesophageal reflux disease (1 October, 2002)
J P Galmiche, F Zerbib

Gastro-oesophageal reflux

Mechanisms of gastro-oesophageal reflux in preterm and term infants with reflux disease (1 October, 2002)
T I Omari, C P Barnett, M A Benninga, R Lontis, L Goodchild, R R Haslam, J Dent, G P Davidson

Helicobacter pylori

Relationship between Helicobacter pylori babA2 status with gastric epithelial cell turnover and premalignant gastric lesions
(1 October, 2002)
J Yu, W K Leung, M Y Y Go, M C W Chan, K F To, E K W Ng, F K L Chan, T K W Ling, S C S Chung, J J Y Sung
Impact of Helicobacter pylori infection and mucosal atrophy on gastric lesions in patients with familial adenomatous polyposis
(1 October, 2002)
S Nakamura, T Matsumoto, Y Kobori, M Iida
Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats (1 October, 2002)
P V Sherwood, J I D Wibawa, J C Atherton, N Jordan, D Jenkins, D A Barrett, P N Shaw, R C Spiller

Motility and visceral sensation

Pan-colonic decrease in interstitial cells of Cajal in patients with slow transit constipation (1 October, 2002)
G L Lyford, C-L He, E Soffer, T L Hull, S A Strong, A J Senagore, L J Burgart, T Young-Fadok, J H Szurszewski, G Farrugia
Double blind, randomised, placebo controlled study of four weeks of lansoprazole for the treatment of functional dyspepsia in Chinese patients (1 October, 2002)
W M Wong, B C Y Wong, W K Hung, Y K Yee, A W C Yip, M L Szeto, F M Y Fung, T S M Tong, K C Lai, W H C Hu, M F Yuen, S K Lam

Small intestine

Effect of stress on the paracellular barrier in the rat ileum (1 October, 2002)
E Mazzon, G C Sturniolo, D Puzzolo, N Frisina, W Fries
Autophagocytosis of the apical membrane in microvillus inclusion disease (1 October, 2002)
K Reinshagen, H Y Naim, K-P Zimmer
Antidiarrhoeal properties of a novel sigma ligand (JO 2871) on toxigenic diarrhoea in mice: mechanisms of action (1 October, 2002)
V Theodorou, M Chovet, H Eutamene, H Fargeau, M Dassaud, M Toulouse, C Bihoreau, F J Roman, L Bueno

Inflammation and inflammatory bowel disease

ICAM-1 and VCAM-1 antisense oligonucleotides attenuate in vivo leucocyte adherence and inflammation in rat inflammatory bowel disease (1 October, 2002)
E Rijcken, C F Krieglstein, C Anthoni, M G Laukoetter, R Mennigen, H U Spiegel, N Senninger, C F Bennett, G Schuermann
Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines (1 October, 2002)
R A J Ransford, M J S Langman
Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation (1 October, 2002)
M T Salmela, T T MacDonald, D Black, B Irvine, T Zhuma, U Saarialho-Kere, S L F Pender

Therapy update

Which 5-ASA? (1 October, 2002)
S P L Travis

Cancer

Flat and depressed colorectal tumours in a southern Swedish population: a prospective chromoendoscopic and histopathological study (1 October, 2002)
S Tsuda, B Veress, E Tóth, F-T Fork
Pk11195, a mitochondrial benzodiazepine receptor antagonist, reduces apoptosis threshold in Bcl-X_L and Mcl-1 expressing human cholangiocarcinoma cells
(1 October, 2002)
A C Okaro, D A Fennell, M Corbo, B R Davidson, F E Cotter
Natural history of primary sclerosing cholangitis and prognostic value of cholangiography in a Dutch population (1 October, 2002)
C Y Ponsioen, S M E Vrouenraets, W Prawirodirdjo, R Rajaram, E A J Rauws, C J J Mulder, J B Reitsma, S H Heisterkamp, G N J Tytgat
Cigarette smoking, appendectomy, and tonsillectomy as risk factors for the development of primary sclerosing cholangitis: a case control study (1 October, 2002)
S A Mitchell, M Thyssen, T R Orchard, D P Jewell, K A Fleming, R W Chapman

Pancreatic disease

Pancreatic stellate cells contribute to regeneration early after acute necrotising pancreatitis in humans (1 October, 2002)
A Zimmermann, B Gloor, A Kappeler, W Uhl, H Friess, M W Büchler
Extracellular signal regulated kinases are key mediators of mitogenic signals in rat pancreatic stellate cells (1 October, 2002)
R Jaster, G Sparmann, J Emmrich, S Liebe

Liver disease

Histological features and HLA class II alleles in hepatitis C virus chronically infected patients with persistently normal alanine aminotransferase levels (1 October, 2002)
C Renou, P Halfon, S Pol, P Cacoub, E Jouve, J P Bronowicki, J P Arpurt, H Rifflet, M Picon, X Causse, V Canva, J Denis, A Tran, M Bourliére, D Ouzan, A Pariente, S Dantin, L Alric, V Cartier, M Reville, S Caillat-Zucman
Regulation of circulating immune complexes by complement receptor type 1 on erythrocytes in chronic viral liver diseases (1 October, 2002)
J Miyaike, Y Iwasaki, A Takahashi, H Shimomura, H Taniguchi, N Koide, K Matsuura, T Ogura, K Tobe, T Tsuji

Case report

Fatal hepatitis B reactivation following discontinuation of nucleoside analogues for chronic hepatitis B (1 October, 2002)
S G Lim, C T Wai, A Rajnakova, T Kajiji, R Guan

Gut file

Collagenous colitis with mucosal tears on endoscopic insufflation: a unique presentation (1 October, 2002)
M Cruz-Correa, F Milligan, F M Giardiello, T M Bayless, M Torbenson, J H Yardley, Frank W Jackson, F Wilson Jackson

Review

Hepatitis C and HIV-1 coinfection (1 October, 2002)
A H Mohsen, P Easterbrook, C B Taylor, S Norris

LETTER

Susceptibility to primary sclerosing cholangitis in Brazil is associated with HLA-DRB1*13 but not with tumour necrosis factor α −308 promoter polymorphism (1 October, 2002)
P L Bittencourt, S A Palacios, E L R Cançado, F J Carrilho, G Porta, J Kalil, A C Goldberg
Slow transit constipation: more than one disease? (1 October, 2002)
C Pehl, T Schmidt, W Schepp
Surveillance for hepatocellular carcinoma in liver cirrhosis: have programmes improved because patients have? (1 October, 2002)
E Giannini, R Testa
Rectal proliferation and alcohol abuse (1 October, 2002)
K Filion
Motilin agonists and dyspepsia: throwing out the baby with the bath water (1 October, 2002)
M Camilleri
Reducing dyspepsia costs in the community (1 October, 2002)
A Duggan, J Westbrook
Causes of obvious jaundice in South West Wales (1 October, 2002)
E H Forrest, J A H Forrest
Behaviour of Crohn's disease according to the Vienna classification (1 October, 2002)
D B Sachar

BOOK REVIEW

Pediatric Gastroenterology and Nutrition in Clinical Practice (1 October, 2002)
L T Weaver
Gastrointestinal Polyps (1 October, 2002)
P Domizio
Upper Gastrointestinal Surgery, 2nd Edn (1 October, 2002)
M Winslet
Challenges in Inflammatory Bowel Disease (1 October, 2002)
D Sachar

CORRECTION

CORRECTION (1 October, 2002) Free

Issue Information